Hao Zhu

1998-2002    Ph.D. degree in Computational Chemistry (Professor Gilles Klopman, thesis advisor) Department of Chemistry, Case Western Reserve University

Thesis Title: Quantitative structure-activity relationship studies of the cancer-related properties of organic molecules

1995-1998    M.S. degree in Applied Chemistry (Professor Nai Shi, thesis advisor) Department of Technical Physics, Peking University, Beijing, China

Thesis Title:  Activity and Conformation Changes of Dihydrofolate Reductase in Reverse Micelles

1991-1995    B.S. degree in Inorganic Chemistry (Professor Yuwen Liu, research advisor) Department of Chemistry, Jilin University, Changchun, Jilin, China

Research Project: Study the Gas Sensitivity of Novel Porphyrin Films

2022

2022-present          Professor, Department of Chemistry and Biochemistry, Rowan University

2021-present          Member, National Academies Committee, National Academy of Sciences (NAS)

2021-present          Adjunct Professor, Division of Environmental & Population Health Biosciences, Environmental and Occupational Health Sciences Institute, Rutgers University, New Brunswick

2020-present          Member, NIEHS Center for Environmental Exposure and Disease, Environmental and Occupational Health Sciences Center, Rutgers University, New Brunswick

2016-present          Member, Joint Graduate Program in Toxicology, Rutgers University, New Brunswick

2020-2022              Professor, Department of Chemistry, Rutgers University, Camden

2011-2022              Member, The Rutgers Center for Computational & Integrative Biology

2017-2020              Graduate Program Director, Department of Chemistry, Rutgers University, Camden

2016-2020              Associate Professor, Department of Chemistry, Rutgers University, Camden

2015-2020              Associate Member, NIEHS Center for Environmental Exposure and Disease, Environmental and Occupational Health Sciences Center, Rutgers University, New Brunswick

2015-2019              Member, Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) at National Institute of Environmental Health Sciences (NIEHS)

2011-2016              Assistant Professor, Department of Chemistry, Rutgers University, Camden

2006-2011              Research Assistant Professor, School of Pharmacy, University of North Carolina, Chapel Hill

2002-2006              Postdoctoral Associate, Department of Chemistry, Case Western Reserve University

                                 Research Advisor:       Gilles Klopman, Ph.D. 

1. American Chemical Society (ACS)

2. Society of Toxicology (SOT)

3. American Society for Cellular and Computational Toxicology

Within the Professions:

2021                        Ad Hoc Reviewer, Dutch Research Council Talent Programme Grant

2021-present          Associate Editor, Ecotoxicology and Environmental Safety

2021                        Ad Hoc Reviewer, European Research Council Consolidator Grant

2021                        Guest editor, Journal of Hazardous Materials

2020                        Guest editor, ACS Sustainable Chemistry & Engineering

2019-present          Associate editor, Frontiers in Toxicology, Computational Toxicology and Informatics

2019                        Ad Hoc Reviewer, NCATS ASPIRE Design Challenge Grant

2017-present          Editorial board member, Ecotoxicology and Environmental Safety

2017-present          ASCCT Annual Meeting Organizing Committee

2016                        Ad Hoc Reviewer, US Army Grant

2016-present          Peer reviewer of US EPA’s draft Provisional Peer-Reviewed Toxicity Values

2015                        Ad Hoc Reviewer, U.S. EPA STAR Fellowship

2014-2019              Member, Acute Toxicity Study Group

Industrial Collaborations/Consultants:

2020-present          Lubrizol, Cleveland, OH

2019-present          ExxonMobil, Clinton, NJ

2011-present          MultiCase Inc., Cleveland, OH

2017                        Sanofi, Bridgewater, NJ

2014                        Sigmapharm Laboratories, Bensalem, PA

2013                        Biofunc Research, Cleveland, OH

Reviewing manuscripts for professional journals:

Nature Machine Intelligence

Nature Climate Change

Nature Communications

Environmental and Health Perspective

Environmental Science and Technology

Chemical Review

Science Advances

Nucleic Acids Research

Environmental Pollution

Nano Today

NanoImpact

Journal of Chemical Information and Modeling

ACS Sustainable Chemistry and Engineering

ACS Infectious Diseases

Journal of Computational Chemistry

Risk Analysis

Toxicological Sciences

Toxicological Research

Chemical Research in Toxicology

Journal of Medicinal Chemistry

Frontier Toxicology

Medicinal Chemistry

SAR and QSAR in Environmental Research

Plos One

Scientific Reports

Toxicology and Applied Pharmacology

Bioorganic and Medicinal Chemistry Letters

Frontiers in Pharmacology

Applied In Vitro Toxicology

Molecular Pharmaceutics

Toxicology Research

Nano-Micro Letters

Ecotoxicology and Environmental Safety

BMC Bioinformatics

Bioorganic and Medicinal Chemistry

Achieve of Toxicology

Chemosphere

npj Computational Materials

Services within the School

Department of Chemistry, Rutgers

2019                        Appointments and Promotions Committee

2019                        Faculty Search Committee

2018                        Appointments and Promotions Committee

2017-2020              Graduate Program Director

2017                        Faculty Search Committee

2013                        Faculty Search Committee

2012                        Faculty Search Committee

Center for Computational and Integrative Biology, Rutgers

2015-present          Undergraduate Curriculum Committee

2013                        Faculty Search Committee

2011-2014              Executive Committee

2011-2014              Admission Committee

Rutgers University:

2016-present          Appointments and Promotions Committee (Natural Science)

2012-2014              Rutgers China Office Advisory Council

Active:

NIEHS (R01ES031080)             Zhu (PI)                           05/19/20 - 02/28/25

Mechanism-Driven Virtual Adverse Outcome Pathway Modeling for Hepatotoxicity. Total cost: $2,271,161

NSF (2211489)       Zhu (leading PI of the multi-PI project)          09/01/2022 - 08/31/2026       

Collaborative Research: III: Medium: New Machine Learning Empowered Nanoinformatics System for Advancing Nanomaterial Design. Total cost: $800,000 ($350,000 to Zhu lab).

NIEHS (R35ES031709)             Zhu (co-I)                        07/16/21- 6/30/29  

Discovering Chemical Activity Networks-Predicting Bioactivity Based on Structure. Subaward to Zhu lab: $576,818, PI: Robyn Tanguay at Oregon State University

ExxonMobil                               Zhu (PI)                           01/01/20 - 12/31/22

Predictive and validated estrogen receptor models. Total cost: $240,005

Completed:

NIEHS (R15ES023148)             Zhu (PI).                          08/09/13 - 07/31/22

Mechanistic evaluation of chemicals that induce oral acute toxicity by novel read-across approaches using public big data. Total cost: $940,888

Lubrizol                                      Zhu (PI)                           05/01/20 - 12/31/20

Develop a hybrid DART model based on both chemical descriptors and biological data obtained from public domain. Total cost: $25,000

Colgate-Palmolive                 Zhu (PI)                           5/1/17–6/30/20

Support read-across study of animal acute toxicity using public biological data. Total cost: $80,000

Rutgers Provost multidisciplinary

research grant                       Zhu (PI)                           1/1/18–12/31/19    

Digital Nano: Developing Virtual Nanomaterial Simulation (VINAS) Toolbox for Intelligent Nanomodeling Total cost: $14,000

The Johns Hopkins Center for       

Alternatives to Animal Testing        Zhu (PI)                           3/1/16–2/28/19

Advance Predictive Modeling of Acute Toxicity by Big Data. Total cost: $70,000

Rutgers ORED-RUN-RBHS Grant

in Big Data Analytics               Zhu (PI)                           7/1/17–6/30/18

Big Data, Modeling and Validation to Advance Hepatotoxicity Prediction. Total cost: $40,000

Rutgers Provost research grant                    Zhu (PI)                           1/1/17–12/31/17       

CIIPro: a new read-across ADME-Tox predictor based on big data tool. Total cost: $3,390

Rutgers University's

Research Council                     Zhu (PI)                           7/1/16–6/30/17

Advance QSAR to Big Data Profiling. Total cost: $3,920

Rutgers University's

Environmental Health Pilot Grant  Zhu (PI)                           1/1/17–3/31/17

From QSAR to big data profiling: the new generation of animal toxicity modeling. Total cost: $4,800

Rutgers University's

Environmental Health Pilot Grant  Zhu (PI)                           7/1/15–2/29/16

From QSAR to big data profiling: the new generation of animal toxicity modeling. Total cost: $15,000

Colgate-Palmolive                 Zhu (PI)                           4/1/13–6/30/15

Profiling chemicals based on public bioassay data for the development of predictive computational acute toxicity model. Total cost: $40,000

Rutgers University's

Research Council                 Zhu (PI)                           4/30/13–5/1/14 Quantitative structure in vitro-in vivo relationship. Total cost: $3,000

Colgate-Palmolive                    Zhu (PI)                           7/1/11–6/30/13

Predictive Quantitative Structure Activity Relationship (QSAR) modeling of reproductive and developmental toxicity using integrated chemical and biological (HTS profiles) descriptors of molecules. Total cost: $35,414

The Johns Hopkins Center for       

Alternatives to Animal Testing        Zhu (PI)                           2/1/08–1/31/11

Use of high throughput screening methods improves computational models for in vivo acute toxicity tests. Total cost: $45,000

EPA (RD832720)                       Zhu (co-PI of project 2)        9/1/05 – 8/31/10

Carolina environmental bioinformatics research center. Total cost: $4,500,000 (co-PI of $725,000 sub-award, PI: Tropsha)